Inhibitors | Comment | Organism | Structure |
---|---|---|---|
pheniprazine | i.e. (1-methyl-2-phenylethyl)hydrazine. Mechanism-based MAO inhibitor | Bos taurus | |
pheniprazine | i.e. (1-methyl-2-phenylethyl)hydrazine. As a reversible inhibitor it is selective towards rat liver MAO-A but the rate of irreversible inhibition of that enzyme is considerably slower; i.e. (1-methyl-2-phenylethyl)hydrazine. Mechanism-based MAO inhibitor | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
mitochondrion | - |
Bos taurus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | P56560 | - |
- |
Rattus norvegicus | P19643 | - |
- |
Rattus norvegicus | P21396 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
liver | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzylamine + H2O + O2 | - |
Rattus norvegicus | benzaldehyde + NH3 + H2O2 | - |
? | |
benzylamine + H2O + O2 | - |
Bos taurus | benzaldehyde + NH3 + H2O2 | - |
? | |
serotonin + H2O + O2 | - |
Rattus norvegicus | (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
monoamine oxidase A | - |
Rattus norvegicus |
monoamine oxidase B | - |
Rattus norvegicus |
monoamine oxidase B | - |
Bos taurus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00004 | - |
pheniprazine | in presence of 3 mM KCN | Rattus norvegicus | |
0.00005 | - |
pheniprazine | in presence of 2 mM KCN | Rattus norvegicus | |
0.00008 | - |
pheniprazine | in presence of 0.0125 mM KCN | Bos taurus | |
0.00009 | - |
pheniprazine | in presence of 0.01 mM KCN | Bos taurus | |
0.00025 | - |
pheniprazine | in presence of 0.007 mM KCN | Bos taurus | |
0.00029 | - |
pheniprazine | in presence of 1 mM KCN | Rattus norvegicus | |
0.00042 | - |
pheniprazine | without KCN | Rattus norvegicus | |
0.00045 | - |
pheniprazine | without KCN | Bos taurus | |
0.00075 | - |
pheniprazine | in presence of 0.005 mM KCN | Rattus norvegicus | |
0.00095 | - |
pheniprazine | in presence of 0.0035 mM KCN | Rattus norvegicus | |
0.00141 | - |
pheniprazine | in presence of 0.0025 mM KCN | Rattus norvegicus | |
0.00245 | - |
pheniprazine | without KCN | Rattus norvegicus |