Literature summary for 1.4.3.4 extracted from

Gabilondo, A.M.; Hostalot, C.; Garibi, J.M.; Meana, J.J.; Callado, L.F.
Monoamine oxidase B activity is increased in human gliomas (2008), Neurochem. Int., 52, 230-234.

Search for more literature for 1.4.3.4

Application

Application	Comment	Organism
medicine	quantification of MAO-B activity may be a useful diagnostic tool for differentiating glial tumours from other types of brain tumours or surrounding normal brain tissue	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P27338	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	MAO-B activity is significantly greater in glioblastoma multiforms than in postmortem control brains or meningiomas. There are no significant differences in MAO-B activity between glioblastoma multiforms and low-grade astrocytomas or anaplastic astrocytomas	Homo sapiens	-
glioma cell	activity selectively increases in MAO-B activity in human gliomas when compared with meningiomas or non-tumoural tissue	Homo sapiens	-
meningioma cell	activity selectively increases in MAO-B activity in human gliomas when compared with meningiomas or non-tumoural tissue	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
phenylethylamine + H2O + O2	-	Homo sapiens	phenylethanal + NH3 + H2O2	-	?

Synonyms

Synonyms	Comment	Organism
MAO-B	-	Homo sapiens
monoamine oxidase B	-	Homo sapiens

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Release 2023.1 (January 2023)