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Literature summary for 1.4.3.4 extracted from

  • Youdim, M.B.H.; Tenne, M.
    Assay and purification of liver monoamine oxidase (1987), Methods Enzymol., 142, 617-627.
    View publication on PubMed
Search for more literature for 1.4.3.4

Inhibitors

Inhibitors Comment Organism Structure
additional information overview: selective inhibitors of form A and B Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
RCH2NH2 + H2O + O2 Rattus norvegicus responsible for the catabolism of various biogenic amine neurotransmitters as well as for the metabolism of certain exogenous amines RCHO + NH3 + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-phenylethylamine + H2O + O2 MAO-B selective substrate Rattus norvegicus 2-phenylethanal + NH3 + H2O2
-
 ?
benzylamine + H2O + O2 MAO-B selective substrate Rattus norvegicus benzaldehyde + NH3 + H2O2
-
 ?
kynuramine + H2O + O2 nonselective substrate Rattus norvegicus 3-(2-aminophenyl)-3-oxopropanal + NH3 + H2O2
-
 ?
RCH2NH2 + H2O + O2 specificity Rattus norvegicus RCHO + NH3 + H2O2
-
 ?
RCH2NH2 + H2O + O2 responsible for the catabolism of various biogenic amine neurotransmitters as well as for the metabolism of certain exogenous amines Rattus norvegicus RCHO + NH3 + H2O2
-
 ?
tyramine + H2O + O2 nonselective substrate Rattus norvegicus (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
More isoforms differ in inhibitor sensitivity Rattus norvegicus
More MAO-A and MAO-B are 2 different isoenzymic forms which differ in substrate specificity, distribution among tissues and their structures Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
flavin flavoprotein Rattus norvegicus
flavin FAD covalently attached to each subunit of the apoprotein Rattus norvegicus