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Literature summary for 1.4.3.4 extracted from

  • McCauley, R.
    Properties of a monoamine oxidase from rat liver mitochondrial outer membranes (1978), Arch. Biochem. Biophys., 189, 8-13.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Clorgyline MAO-A highly sensitive and MAO-B less sensitive to inhibition; poor inhibition Rattus norvegicus
Deprenyl MAO-B sensitive Rattus norvegicus
Pargyline MAO-B sensitive Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information Km of mitochondrial outer membrane and purified enzyme Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrial outer membrane
-
Rattus norvegicus 5741
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
65000
-
x * 65000, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.8
-
-
Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-phenylethylamine + H2O + O2
-
Rattus norvegicus 2-phenylethanal + NH3 + H2O2
-
?
benzylamine + H2O + O2
-
Rattus norvegicus benzaldehyde + NH3 + H2O2
-
?
dopamine + H2O + O2
-
Rattus norvegicus (3,4-dihydroxyphenyl)acetaldehyde + NH3 + H2O2
-
?
RCH2NH2 + H2O + O2 norepinephrine Rattus norvegicus RCHO + NH3 + H2O2
-
?
RCH2NH2 + H2O + O2 octopamine Rattus norvegicus RCHO + NH3 + H2O2
-
?
serotonin + H2O + O2
-
Rattus norvegicus (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
?
tyramine + H2O + O2
-
Rattus norvegicus (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2
-
?

Subunits

Subunits Comment Organism
? x * 65000, SDS-PAGE Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
flavin
-
Rattus norvegicus