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Literature summary for 1.4.3.22 extracted from

  • Bardsley, W.G.; Crabbe, M.J.C.; Shindler, J.S.
    Kinetics of the diamine oxidase reaction (1973), Biochem. J., 131, 459-469.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
H2O2 uncompetitive vs. p-dimethylaminomethylbenzylamine Sus scrofa
NH3 competitive vs. p-dimethylaminomethylbenzylamine, uncompetitive vs. O2 Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Reaction

Reaction Comment Organism Reaction ID
histamine + H2O + O2 = (imidazol-4-yl)acetaldehyde + NH3 + H2O2 mechanism Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
p-dimethylaminomethylbenzylamine + H2O + O2
-
Sus scrofa p-dimethylaminomethylbenzaldehyde + NH3 + H2O2
-
?
RCH2NH2 + H2O + O2
-
Sus scrofa RCHO + NH3 + H2O2
-
?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.3
-
H2O2 vs. p-dimethylaminomethylbenzylamine Sus scrofa
0.5
-
H2O2 vs. O2 Sus scrofa
33.8
-
NH3 vs. p-dimethylaminomethylbenzylamine Sus scrofa
36
-
NH3 vs. O2 Sus scrofa