Inhibitors | Comment | Organism | Structure |
---|---|---|---|
nitric oxide | irreversible inhibitor | Euphorbia characias | |
tyramine | irreversible inhibitor | Euphorbia characias |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | the enzyme contains one non-blue copper type 2 ion as an inorganic cofactor | Euphorbia characias |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
74000 | - |
2 * 74000, calculated from amino acid sequence | Euphorbia characias |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Euphorbia characias | Q9SW90 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
latex | - |
Euphorbia characias | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme oxidizes arginine to ammonia, urea, hydrogen peroxide and glutamate-5-semialdehyde which spontaneously cyclizes yielding DELTA1-pyrroline-5-carboxylic acid | Euphorbia characias | ? | - |
? | |
ornithine + H2O + O2 | ornithine can be transformed in glutamate-5-semialdehyde spontaneously cyclizes yielding DELTA1-pyrroline-5-carboxylic acid | Euphorbia characias | ? | - |
? | |
putrescine + H2O + O2 | putrescine can be oxidatively deaminated by the enzyme to corresponding aldehyde that spontaneously cyclizes yielding DELTA1-pyrroline | Euphorbia characias | ? | - |
? | |
spermidine + H2O + O2 | good substrate. The oxidation of spermidine yields to the liberation of ammonia, hydrogen peroxide and the corresponding aldehyde that spontaneously cyclizes yielding first 1-(3-aminopropyl)pyrroliniun and, thereafter, 1,5-diazobicyclononane | Euphorbia characias | ? + NH3 + H2O2 | - |
? | |
spermine + H2O + O2 | good substrate | Euphorbia characias | ? + NH3 + H2O2 | - |
? | |
tyramine + H2O + O2 | during this reaction, an irreversible inactivation of the enzyme occurs | Euphorbia characias | 4-hydroxyphenylacetaldehyde + NH3 + H2O2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | 2 * 74000, calculated from amino acid sequence | Euphorbia characias |
Synonyms | Comment | Organism |
---|---|---|
copper/quinone containing amine oxidase | - |
Euphorbia characias |
ELAO | - |
Euphorbia characias |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
2,4,5-trihydroxyphenylalanine quinone | - |
Euphorbia characias |