Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of AOC3-KO mice which show white adipose tissue with lower CD45 mRNA levels and fewer CD45+ leukocytes and diminished infiltration by T cells, macrophages, natural killer, and natural killer T cells, the phenotype is not rescued by human SSAO/VAP-1 expression on adipocytes under the control of aP2, overview | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Mus musculus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
female and male C57BL/6 mice, gene AOC3 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipocyte | - |
Mus musculus | - |
endothelial cell | - |
Mus musculus | - |
white adipose tissue | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
semicarbazide-sensitive amine oxidase | - |
Mus musculus |
SSAO | - |
Mus musculus |
SSAO/VAP-1 | - |
Mus musculus |
VAP-1 | - |
Mus musculus |
vascular adhesion protein-1 | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | AOC3 knockout mice show white adipose tissue with lower CD45 mRNA levels and fewer CD45+ leukocytes and diminished infiltration by T cells, macrophages, natural killer, and natural killer T cells | down |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme deficiency reduces leukocyte infiltration into adipose tissue and favors fat deposition | Mus musculus |
physiological function | the enzyme is present on the endothelial cell surface where it is involved in leukocyte extravasation | Mus musculus |