Application | Comment | Organism |
---|---|---|
medicine | an extracellular matrix (ECM)-targeting nanotherapeutic is engineered using a lipid-based nanoparticle chemically linked to an inhibitor of the ECM-related enzyme, lysyl oxidase 1 (LOX), that inhibits the crosslinking of elastin and collagen fibers. When the conjugated vesicles are loaded with the chemotherapeutic epirubicin, superior inhibition of triple negative breast cancer (TNBC) cell growth is observed both in vitro and in vivo | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q08397 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
lysyl oxidase 1 | - |
Homo sapiens |