Literature summary for 1.4.3.13 extracted from

Hurtado, P.A.; Vora, S.; Sume, S.S.; Yang, D.; St Hilaire, C.; Guo, Y.; Palamakumbura, A.H.; Schreiber, B.M.; Ravid, K.; Trackman, P.C.
Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation (2008), Biochem. Biophys. Res. Commun., 366, 156-161.

Search for more literature for 1.4.3.13

Application

Application	Comment	Organism
synthesis	required for the normal biosynthesis and maturation of collagen and elastin	Rattus norvegicus

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in TREX 293 cells	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	TNF-alpha-stimulated matrix metalloproteinase-9 expression and Erk1/2 activation are both significantly inhibited by LOX-PP	Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
35000	-	LOX propeptide, SDS-PAGE	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
nickel affinity column chromatography and ultrafiltration	Rattus norvegicus

Source Tissue

Source Tissue	Comment	Organism	Textmining
aortic smooth muscle cell	-	Rattus norvegicus	-
artery	highly expressed in vascular lesions	Rattus norvegicus	-
smooth muscle	-	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
LOX-PP	-	Rattus norvegicus
lysyl oxidase propetide	has biological activity as a tumor suppressor, and it inhibits Erk1/2 Map kinase activation	Rattus norvegicus

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Release 2023.1 (January 2023)