Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.4.1.9 extracted from

  • Baker, P.J.; Turnbull, A.P.; Sedelnikova, S.E.; Stillman, T.J.; Rice, D.W.
    A role for quaternary structure in the substrate specificity of leucine dehydrogenase (1995), Structure, 3, 693-705.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Lysinibacillus sphaericus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Leu + H2O + NAD+
-
Lysinibacillus sphaericus 4-methyl-2-oxopentanoate + NH3 + NADH
-
r

Cofactor

Cofactor Comment Organism Structure
NAD+ the nicotinamide ring of the NAD+ cofactor binds deeply in the cleft that separates the two domains of each subunit Lysinibacillus sphaericus
NADH
-
Lysinibacillus sphaericus