Literature summary for 1.4.1.24 extracted from

White, R.H.
L-Aspartate semialdehyde and a 6-deoxy-5-ketohexose 1-phosphate are the precursors to the aromatic amino acids in Methanocaldococcus jannaschii (2004), Biochemistry, 43, 7618-7627.

Search for more literature for 1.4.1.24

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21-CodonPlus (DE3)-RIL cells	Methanocaldococcus jannaschii

Organism

Organism	UniProt	Comment	Textmining
Methanocaldococcus jannaschii	P81230	-	-
Methanocaldococcus jannaschii DSM 2661	P81230	-	-

Purification (Commentary)

Purification (Comment)	Organism
heat precipitation and Sephadex G-25 gel filtration	Methanocaldococcus jannaschii

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+	2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate undergoes a NAD+-dependent oxidative deamination to produce 3,7-dideoxy-D-threo-hept-2,6-diulosonic acid which cyclizes to 3-dehydroquinate	Methanocaldococcus jannaschii	3-dehydroquinate + NH3 + NADH + H+	-	?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+	2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate undergoes a NAD+-dependent oxidative deamination to produce 3,7-dideoxy-D-threo-hept-2,6-diulosonic acid which cyclizes to 3-dehydroquinate	Methanocaldococcus jannaschii DSM 2661	3-dehydroquinate + NH3 + NADH + H+	-	?

Synonyms

Synonyms	Comment	Organism
MJ1249 protein	-	Methanocaldococcus jannaschii

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Release 2023.1 (January 2023)