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Literature summary for 1.4.1.2 extracted from
- Identification of the residue responsible for catalysing regeneration of activity in the inactive glutamate dehydrogenase mutant D165N (2005), FEBS Lett., 579, 2830-2832.
Application
| Application | Comment | Organism |
|---|---|---|
| additional information | reactivation of D165N is a consequence of the catalytic chemistry of the enzymes active site | [Clostridium] symbiosum |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli TG1 | [Clostridium] symbiosum |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| D165N/K125A | correctly folded, no significant deamidation | [Clostridium] symbiosum |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5,5'-dithiobis(2-nitrobenzoate) | - |
[Clostridium] symbiosum |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| [Clostridium] symbiosum | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| gel filtration | [Clostridium] symbiosum |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glutamate dehydrogenase | - |
[Clostridium] symbiosum |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | protects against targeting the Cys320 in the active site by 5,5'-dithiobis(2-nitrobenzoate) | [Clostridium] symbiosum | |
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