Crystallization (Comment) | Organism |
---|---|
crystals of the ternary complex formed from the enzyme, NADP+ and the inhibitor L-2-amino-6-methylene-pimelate, 2.1 A resolution | Corynebacterium glutamicum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-2-amino-6-methylene-pimelate | competitive inhibition | Lysinibacillus sphaericus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Corynebacterium glutamicum | - |
- |
- |
Lysinibacillus sphaericus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H | - |
Lysinibacillus sphaericus | meso-2,6-diaminoheptanedioate + H2O + NAD(P)+ | - |
r | |
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H | - |
Corynebacterium glutamicum | meso-2,6-diaminoheptanedioate + H2O + NAD(P)+ | - |
r |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Lysinibacillus sphaericus | |
NADPH | - |
Corynebacterium glutamicum |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.005 | - |
L-2-amino-6-methylene-pimelate | - |
Lysinibacillus sphaericus |