Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-lysine + NAD+ | Ruegeria pomeroyi | - |
1,2-didehydropiperidine-2-carboxylate + NH3 + NADH + H+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ruegeria pomeroyi | - |
gene lysdh | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-lysine + NAD+ | - |
Ruegeria pomeroyi | 1,2-didehydropiperidine-2-carboxylate + NH3 + NADH + H+ | - |
r | |
additional information | LysDH directly converts L-lysine to alpha-aminoadipic-delta-semialdehyde | Ruegeria pomeroyi | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LysDH | - |
Ruegeria pomeroyi |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Ruegeria pomeroyi | |
NADH | - |
Ruegeria pomeroyi |
Organism | Comment | Expression |
---|---|---|
Ruegeria pomeroyi | gene lysdh is not upregulated under salt stress, in contrast to several other enzymes from the lysine-to-alpha-aminoadipic-delta-semialdehyde pathways, but is upregulated by addition of exogenous lysine | additional information |
General Information | Comment | Organism |
---|---|---|
evolution | genomic organization and functional role of lysine catabolic pathways among prokaryotes, overview | Ruegeria pomeroyi |
physiological function | the enzyme is part of the lysine-to alpha-aminoadipic-delta-semialdehyde-pathway, that has a broad evolutionary importance in osmotic stress resistance | Ruegeria pomeroyi |