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Literature summary for 1.3.99.5 extracted from

  • Amory, J.K.; Anawalt, B.D.; Matsumoto, A.M.; Page, S.T.; Bremner, W.J.; Wang, C.; Swerdloff, R.S.; Clark, R.V.
    The effect of 5alpha-reductase inhibition with dutasteride and finasteride on bone mineral density, serum lipoproteins, hemoglobin, prostate specific antigen and sexual function in healthy young men (2008), J. Urol., 179, 2333-2338.
    View publication on PubMedView publication on EuropePMC
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Inhibitors

Inhibitors Comment Organism Structure
dutasteride inhibits type 1 5alpha-reductase Homo sapiens
finasteride inhibits type 2 5alpha-reductase Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
testosterone + reduced acceptor Homo sapiens
-
 5alpha-dihydrotestosterone + acceptor
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
testosterone + reduced acceptor
-
 Homo sapiens 5alpha-dihydrotestosterone + acceptor
-
 ?

Synonyms

Synonyms Comment Organism
type 1 5alpha-reductase
-
 Homo sapiens
type 2 5alpha-reductase
-
 Homo sapiens