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Literature summary for 1.3.99.4 extracted from
- Bacterial oxidation of steroids. II. Studies on the enzymatic mechanism of ring A dehydrogenation (1959), J. Biol. Chem., 234, 2014-2021.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| CuSO4 | - |
Comamonas testosteroni |  |
| estrone | slight | Comamonas testosteroni | |
| HgCl2 | - |
Comamonas testosteroni | |
| MnSO4 | - |
Comamonas testosteroni | |
| o-Iodosobenzoate | - |
Comamonas testosteroni | |
| p-chloromercuribenzoate | - |
Comamonas testosteroni | |
| p-chloromercuriphenylsulfonate | - |
Comamonas testosteroni | |
| ZnSO4 | - |
Comamonas testosteroni | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| particle-bound | associated with fine particulate structures | Comamonas testosteroni | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Comamonas testosteroni | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Comamonas testosteroni |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 11alpha-hydroxy-testosterone + acceptor | - |
Comamonas testosteroni | 11alpha,17beta-dihydroxyandrost-1,4-diene-3-one + reduced acceptor | - |
? | |
| 11beta-hydroxy-4-androstene-3,17-dione + acceptor | - |
Comamonas testosteroni | 11beta-hydroxy-1,4-androstene-3,17-dione + reduced acceptor | - |
? | |
| 17alpha-hydroxy-progesterone + acceptor | 4-pregnene-17alpha-ol-3,20-dione | Comamonas testosteroni | 1,4-pregnene-17alpha-ol-3,20-dione + reduced acceptor | - |
? | |
| 17alpha-methyltestosterone + acceptor | - |
Comamonas testosteroni | 17alpha-methylandrost-1,4-diene-3-one + reduced acceptor | - |
? | |
| 4-androstene-3,17-dione + acceptor | - |
Comamonas testosteroni | 1,4-androstene-3,17-dione + reduced acceptor | - |
ir | |
| 4-pregnene-3,20-dione + acceptor | - |
Comamonas testosteroni | 1,4-pregnene-3,20 dione + reduced acceptor | - |
? | |
| deoxycorticosterone + acceptor | 4-pregnene-21-ol-3,20-dione | Comamonas testosteroni | 1,4-pregnene-21-ol-3,20-dione + reduced acceptor | - |
? | |
| additional information | acceptor: phenazine methosulfate | Comamonas testosteroni | ? | - |
? | |
| testosterone + acceptor | - |
Comamonas testosteroni | 17beta-hydroxyandrost-1,4-diene-3-one + reduced acceptor | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Comamonas testosteroni |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9.5 | - |
- |
Comamonas testosteroni |
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Release 2023.1 (January 2023)
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