Cloned (Comment) | Organism |
---|---|
LCAD real-time RT-PCR expression analysis in different tissues | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2,6-dimethylheptanoyl-CoA + oxidized flavin | Homo sapiens | specific LCAD substrate | 2,3-dehydro-2,6-dimethylheptanoyl-CoA + reduced flavin | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | very low enzyme content | Homo sapiens | - |
liver | very low enzyme content | Homo sapiens | - |
additional information | LCAD real-time RT-PCR expression analysis in different tissues | Homo sapiens | - |
skeletal muscle | vastus lateralis, LCAD content compared to that of very-long chain acyl-CoA dehydrogenase, VLCAD, and medium chain acyl-CoA dehydrogenase, MCAD. mRNA presence of LCAD in human skeletal muscle is significantly less than VLCAD and MCAD, LCAD protein is almost undetectable, overview | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2,6-dimethylheptanoyl-CoA + oxidized flavin | specific LCAD substrate | Homo sapiens | 2,3-dehydro-2,6-dimethylheptanoyl-CoA + reduced flavin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LCAD | - |
Homo sapiens |
long-chain acyl-CoA dehydrogenase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
flavin | a flavoenzyme | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | long-chain acyl-CoA dehydrogenase is a mitochondrial flavoenzyme that plays no role in long-chain fatty acid beta-oxidation in heart, liver, and skeletal muscle, overview | Homo sapiens |