Application | Comment | Organism |
---|---|---|
additional information | acyl-CoA dehydrogenase LipB is involved in the introduction of the unusual Dcis3 double bond into the acyl residue of friulimicin | Actinoplanes friuliensis |
Cloned (Comment) | Organism |
---|---|
cloned on plasmid pEHEX2 and heterologous expression in Streptomyces lividans T7 | Actinoplanes friuliensis |
Protein Variants | Comment | Organism |
---|---|---|
additional information | lipB insertion mutant, zone of growth inhibition around mutant is only ca. 62% of the wild-type inhibition zone indicating a reduced friulimicin production or a modified, less biologically active friulimicin production | Actinoplanes friuliensis |
additional information | mutant strain deleted in the pim gene cluster, grows at about half the rate of the wild-type parent when benzoate or pimelate is supplied as the sole carbon source, grows five times more slowly than the wild-type on the C14 dicarboxylic acid tetradecanedioate, but is unimpaired in growth on the C8-fatty acid caprylate | Rhodopseudomonas palustris |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Actinoplanes friuliensis | - |
- |
- |
Rhodopseudomonas palustris | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Actinoplanes friuliensis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | beta-oxidation enzymes encoded by the pim gene cluster including acyl CoA dehydrogenase are active with medium-chain-length dicarboxylic acids | Rhodopseudomonas palustris | ? | - |
? | |
additional information | involved in the formation of unsaturated fatty acid | Actinoplanes friuliensis | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
acyl CoA dehydrogenase | - |
Rhodopseudomonas palustris |
acyl-CoA dehydrogenase | - |
Actinoplanes friuliensis |
LipB | - |
Actinoplanes friuliensis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Actinoplanes friuliensis |