Literature summary for 1.3.5.2 extracted from

McLean, J.E.; Neidhardt, E.A.; Grossman, T.H.; Hedstrom, L.
Multiple inhibitor analysis of the brequinar and leflunomide binding sites on human dihydroorotate dehydrogenase (2001), Biochemistry, 40, 2194-2200.

Inhibitors

Inhibitors	Comment	Organism	Structure
2-hydroxyethylidene-cyanoacetic acid 4-trifluoromethyl anilide	noncompetitive versus ubiquinone, uncompetitive versus dihydroorotate, study of kinetics	Homo sapiens
brequinar sodium	competitive versus ubiquinone, uncompetitive versus dihydroorotate, study of kinetics	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

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Release 2023.1 (January 2023)