Application | Comment | Organism |
---|---|---|
molecular biology | the relevance of modifications in Alternaria alternata AaSdhB sequence in conferring boscalid resistance is discussed | Alternaria alternata |
Protein Variants | Comment | Organism |
---|---|---|
H277R | the molecular basis of boscalid-resistant phenotypes in Alternaria alternata is elucidated. Furthermore, the cross-resistance pattern between boscalid and carboxin in these isolates is investigated. The iron-sulfur subunit of SDHB is targeted for analysis. Sequence comparison of resistant isolates with those of the wild-type isolates show that a single point mutation exist in fungicide-resistant isolates. This mutation leads to a substitution of a highly conserved histidine residue, located in a region associated with the (3Fe-4S) high-potential non-heme iron sulphur-redox (S3) center to either H277Y or H277R | Alternaria alternata |
H277Y | the molecular basis of boscalid-resistant phenotypes in Alternaria alternata is elucidated. Furthermore, the cross-resistance pattern between boscalid and carboxin in these isolates is investigated. The iron-sulfur subunit of SDHB is targeted for analysis. Sequence comparison of resistant isolates with those of the wild-type isolates show that a single point mutation exist in fungicide-resistant isolates. This mutation leads to a substitution of a highly conserved histidine residue, located in a region associated with the (3Fe-4S) high-potential non-heme iron sulphur-redox (S3) center to either H277Y or H277R | Alternaria alternata |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
carboxin | - |
Alternaria alternata |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
3Fe-4S center | the iron-sulfur subunit of SDHB is targeted for analysis. Sequence comparison of resistant isolates with those of the wild-type isolates show that a single point mutation exist in fungicide-resistant isolates. This mutation leads to a substitution of a highly conserved histidine residue, located in a region associated with the (3Fe-4S) high-potential non-heme iron sulphur-redox (S3) center to either H277Y or H277R | Alternaria alternata |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Alternaria alternata | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
AaSdhB | - |
Alternaria alternata |
succinate dehydrogenase | - |
Alternaria alternata |