Literature summary for 1.3.5.1 extracted from

Ando, A.; Sakuradani, E.; Horinaka, K.; Ogawa, J.; Shimizu, S.
Transformation of an oleaginous zygomycete Mortierella alpina 1S-4 with the carboxin resistance gene conferred by mutation of the iron-sulfur subunit of succinate dehydrogenase (2009), Curr. Genet., 55, 349-356.

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Application

Application	Comment	Organism
biotechnology	a new host-vector system for Mortierella alpina 1S-4, zygomycetes, on the basis of self-cloning for the industrial application of Mortierella transformants is developed. Transformants expressing the Escherichia coli uidA gene encoding beta-glucuronidase by using the mutant H243L as the selectable marker (leading to to carboxin resistance)	Mortierella alpina

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Mortierella alpina 1S-4	Mortierella alpina

Protein Variants

Protein Variants	Comment	Organism
H243L	an amino-acid substitution of a highly conserved histidine residue within the third cysteine-rich cluster of SdhB replaced by a leucine residue confers carboxin resistance to the organism	Mortierella alpina

Metals/Ions

Metals/Ions	Comment	Organism	Structure
3Fe-4S center	sdhB gene encodes an ironsulfur subunit of succinate dehydrogenase	Mortierella alpina

Organism

Organism	UniProt	Comment	Textmining
Mortierella alpina	C4T9C3	-	-

Synonyms

Synonyms	Comment	Organism
SDHB	-	Mortierella alpina
SDHB	sdhB gene encodes an iron-sulfur subunit of succinate dehydrogenase	Mortierella alpina

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Release 2023.1 (January 2023)