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Literature summary for 1.3.5.1 extracted from
- Direct and mediated electron transfer between intact succinate:quinone oxidoreductase from Bacillus subtilis and a surface modified gold electrode reveals redox state-dependent conformational changes (2008), Biochim. Biophys. Acta, 1777, 1203-1210.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-n-heptyl-4 hydroxyquinoline N-oxide | a specific inhibitor, i.e. HQNO, which binds to quinone binding site Qd in SQR | Bacillus subtilis |  |
| oxaloacetate | an inhibitor of the succinate binding site | Bacillus subtilis | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Bacillus subtilis | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinate + ubiquinone | Bacillus subtilis | - |
fumarate + ubiquinol | - |
? | |
| succinate + ubiquinone | Bacillus subtilis 3G18 | - |
fumarate + ubiquinol | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | - |
harbors the entire sdh operon on a low copy number plasmid | - |
| Bacillus subtilis 3G18 | - |
harbors the entire sdh operon on a low copy number plasmid | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| enzyme from membranes of strain 3G18, expressed from low copy plasmid | Bacillus subtilis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | electronic communication between purified SQR and a surface modified gold capillary electrode, redox titrations, overview | Bacillus subtilis | ? | - |
? | |
| additional information | electronic communication between purified SQR and a surface modified gold capillary electrode, redox titrations, overview | Bacillus subtilis 3G18 | ? | - |
? | |
| succinate + 2,6-dichlorophenolindophenol | - |
Bacillus subtilis | fumarate + reduced 2,6-dichlorophenolindophenol | - |
? | |
| succinate + 2,6-dichlorophenolindophenol | - |
Bacillus subtilis 3G18 | fumarate + reduced 2,6-dichlorophenolindophenol | - |
? | |
| succinate + ubiquinone | - |
Bacillus subtilis | fumarate + ubiquinol | - |
? | |
| succinate + ubiquinone | - |
Bacillus subtilis 3G18 | fumarate + ubiquinol | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | the enzyme from Bacillus subtilis consists of two hydrophilic protein subunits comprising succinate dehydrogenase, and a di-heme membrane anchor protein harboring two putative quinone binding sites, overview | Bacillus subtilis |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SQR | - |
Bacillus subtilis |
| succinate:quinone oxidoreductase | - |
Bacillus subtilis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Bacillus subtilis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| 2,6-dichlorophenolindophenol | - |
Bacillus subtilis | |
| heme | in a di-heme membrane anchor protein harboring two putative quinone binding sites | Bacillus subtilis | |
| ubiquinone | two putative binding sites in the di-heme membrane anchoring protein | Bacillus subtilis | |
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