Literature summary for 1.3.3.6 extracted from

Zeng, J.; Wu, L.; Zhang, X.; Liu, Y.; Deng, G.; Li, D.
Oct-2-en-4-ynoyl-CoA as a specific inhibitor of acyl-CoA oxidase (2008), Org. Lett., 10, 4287-4290.

Search for more literature for 1.3.3.6

Cloned(Commentary)

Cloned (Comment)	Organism
-	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
oct-2-en-4-ynoyl-CoA	irreversible inactivation, pH dependent, higher under basic condition	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
peroxisome	-	Rattus norvegicus	5777	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Rattus norvegicus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acyl-CoA + O2	assay at 25°C	Rattus norvegicus	trans-2-enoyl-CoA + H2O2	-	ir

Synonyms

Synonyms	Comment	Organism
ACO	-	Rattus norvegicus
Acyl-CoA oxidase	-	Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
25	-	assay at	Rattus norvegicus

Cofactor

Cofactor	Comment	Organism	Structure
FAD	-	Rattus norvegicus

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.045	-	oct-2-en-4-ynoyl-CoA	-	Rattus norvegicus

General Information

General Information	Comment	Organism
physiological function	involved in fatty acid oxidation, essential energy generation	Rattus norvegicus

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Release 2023.1 (January 2023)