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Literature summary for 1.3.3.3 extracted from

  • Guo, C.Y.; Wu, G.H.; Xing, J.; Li, W.Q.; Tang, D.Z.; Cui, B.M.
    A mutation in a coproporphyrinogen III oxidase gene confers growth inhibition, enhanced powdery mildew resistance and powdery mildew-induced cell death in Arabidopsis (2013), Plant Cell Rep., 32, 687-702.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene LIN2, construction of transgenic plants expressing the mutant LIN2 gene using Agrobacterium tumefaciens strain GV3101 transfection Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information spontaneous lesion formation mutant lin2-2 Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
-
Arabidopsis thaliana 9507
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
coproporphyrinogen III + O2 + H+ Arabidopsis thaliana
-
protoporphyrinogen IX + CO2 + H2O
-
?
coproporphyrinogen III + O2 + H+ Arabidopsis thaliana Col-0
-
protoporphyrinogen IX + CO2 + H2O
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q9LR75
-
-
Arabidopsis thaliana Q9LR75 gene LIN2
-
Arabidopsis thaliana Col-0 Q9LR75 gene LIN2
-

Source Tissue

Source Tissue Comment Organism Textmining
cotyledon
-
Arabidopsis thaliana
-
flower
-
Arabidopsis thaliana
-
leaf
-
Arabidopsis thaliana
-
additional information not in seeds, expression analysis, overview Arabidopsis thaliana
-
root
-
Arabidopsis thaliana
-
silique
-
Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
coproporphyrinogen III + O2 + H+
-
Arabidopsis thaliana protoporphyrinogen IX + CO2 + H2O
-
?
coproporphyrinogen III + O2 + H+
-
Arabidopsis thaliana Col-0 protoporphyrinogen IX + CO2 + H2O
-
?

Synonyms

Synonyms Comment Organism
coproporphyrinogen III oxidase
-
Arabidopsis thaliana
CPO
-
Arabidopsis thaliana
LIN2
-
Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction spontaneous lesion formation mutant lin2-2. The lin2-2 mutation confers growth inhibition, enhanced powdery mildew resistance, and powdery mildew (Golovinomyces cichoracearum strain UCSC1)-induced cell death, as well as spontaneous cell death dependent on salicylic acid, in Arabidopsis thaliana, phenotye, detailed overview. The lin2-2 mutant also displays enhanced resistance to Hyaloperonospora arabidopsidis Noco2, and lin2-2 mutants exhibit enhanced ethylene-induced senescence. The edr1 mutation enhances the lin2-2 phenotype Arabidopsis thaliana
malfunction the lin2-2 mutant exhibits enhanced ethylene-induced senescence. Additionally, the chlorophyll level is significantly lower in lin2-2 than in the wild type when treated with ethylene for 3 days Arabidopsis thaliana
metabolism LIN2 encodes coproporphyrinogen III oxidase, CPO, a key enzyme of the tetrapyrrole biosynthesis pathway Arabidopsis thaliana