Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.3.3.3 extracted from

  • Hsu, W.P.; Miller, G.W.
    Coproporphyrinogenase in tobacco (Nicotiana tabacum L.) (1970), Biochem. J., 117, 215-220.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline inhibition at 1 mM Nicotiana tabacum
Co2+ inhibition above 5 mM Nicotiana tabacum
Cu2+ inhibition at 0.1 mM Nicotiana tabacum
EDTA inhibition at 1 mM Nicotiana tabacum
Fe2+ inhibition above 0.1 mM Nicotiana tabacum
Mn2+ inhibition above 5 mM Nicotiana tabacum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.036
-
Coproporphyrinogen-III
-
Nicotiana tabacum

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Nicotiana tabacum 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ activation up to 0.1 mM, beyond inhibitory Nicotiana tabacum
Fe2+ enhanced activity by increasing concentrations up to 0.5 mM, beyond inhibitory Nicotiana tabacum
Mn2+ activation up to 0.1 mM, beyond inhibitory Nicotiana tabacum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
coproporphyrinogen-III + O2 + 2 H+ Nicotiana tabacum
-
protoporphyrinogen-IX + 2 CO2 + 2 H2O
-
?

Organism

Organism UniProt Comment Textmining
Nicotiana tabacum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
69fold purificationcalcium phosphate gel Nicotiana tabacum

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
Nicotiana tabacum
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.002
-
-
Nicotiana tabacum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
coproporphyrinogen-III + O2 + 2 H+
-
Nicotiana tabacum protoporphyrinogen-IX + 2 CO2 + 2 H2O
-
?