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Literature summary for 1.3.3.11 extracted from

  • Magnusson, O.T.; RoseFigura, J.M.; Toyama, H.; Schwarzenbacher, R.; Klinman, J.P.
    Pyrroloquinoline quinone biogenesis: characterization of PqqC and its H84N and H84A active site variants (2007), Biochemistry, 46, 7174-7186.
    View publication on PubMed
Search for more literature for 1.3.3.11

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Klebsiella pneumoniae

Protein Variants

Protein Variants Comment Organism
H84A active site mutant with reduced activity Klebsiella pneumoniae
H84N active site mutant with reduced activity Klebsiella pneumoniae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28000
-
 SDS-PAGE Klebsiella pneumoniae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Klebsiella pneumoniae catalyzes the final step of PQQ formation, which involves a ring closure and an overall eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic acid in the absence of a redox-active metal or cofactor ?
-
 ?

Organism

Organism UniProt Comment Textmining
Klebsiella pneumoniae
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Q-Sepharose column chromatography and Ultrogel AcA54 gel filtration Klebsiella pneumoniae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic acid + O2
-
 Klebsiella pneumoniae 4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + H2O2 + H2O
-
 ?
additional information catalyzes the final step of PQQ formation, which involves a ring closure and an overall eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic acid in the absence of a redox-active metal or cofactor Klebsiella pneumoniae ?
-
 ?

Synonyms

Synonyms Comment Organism
PqqC
-
 Klebsiella pneumoniae