Cloned (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cyclovalone | - |
Rattus norvegicus | |
progesterone | - |
Rattus norvegicus | |
quercetin | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.001 | - |
15-oxoprostaglandin E1 | 30°C | Rattus norvegicus | |
0.11 | - |
ethyl vinyl ketone | 30°C | Rattus norvegicus | |
0.12 | - |
4-hydroxy-2-nonenal | 30°C | Rattus norvegicus | |
0.15 | - |
acrolein | 30°C | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
n-alkanal + NAD(P)+ | Rattus norvegicus | role in detoxication | alk-2-enal + NAD(P)H | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Storage Stability | Organism |
---|---|
-80°C, no loss of activity for 8 months | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
15-oxoprostaglandin E1 + NAD(P)H | - |
Rattus norvegicus | ? + NAD(P)+ | - |
? | |
4-hydroxy-(2E)-nonenal + NAD(P)H | - |
Rattus norvegicus | 4-hydroxynonylaldehyde + NAD(P)+ | - |
? | |
benzylidine acetone + NAD(P)H | reduction of alpha,beta-double bond | Rattus norvegicus | ? + NAD(P)+ | - |
? | |
ethyl vinyl ketone + NAD(P)H | - |
Rattus norvegicus | diethylketone + NAD(P)+ | - |
? | |
methyl vinyl ketone + NAD(P)H | - |
Rattus norvegicus | dimethylketone + NAD(P)+ | - |
? | |
additional information | reduction of the alpha,beta-carbon-carbon double bond to a single bond, broad substrate specificity | Rattus norvegicus | ? | - |
? | |
n-alkanal + NAD(P)+ | - |
Rattus norvegicus | alk-2-enal + NAD(P)H | - |
? | |
n-alkanal + NAD(P)+ | role in detoxication | Rattus norvegicus | alk-2-enal + NAD(P)H | - |
? | |
propenal + NAD(P)H | synonym: acrolein | Rattus norvegicus | propanal + NAD(P)+ | - |
? | |
trans,trans-2,4-alkadienal + NAD(P)H | - |
Rattus norvegicus | ? + NAD(P)+ | - |
? | |
trans-2-alkenal + NAD(P)H | - |
Rattus norvegicus | alkanal + NAD(P)+ | - |
? | |
trans-4-hydroxy-2-alkenal + NAD(P)H | - |
Rattus norvegicus | 4-hydroxyalkanal + NAD(P)+ | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Rattus norvegicus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
3.67 | - |
acrolein | 30°C | Rattus norvegicus | |
40 | - |
15-oxoprostaglandin E1 | 30°C | Rattus norvegicus | |
66.7 | - |
4-hydroxy-2-nonenal | 30°C | Rattus norvegicus | |
160 | - |
ethyl vinyl ketone | 30°C | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Rattus norvegicus |