Application | Comment | Organism |
---|---|---|
medicine | DHCR24 plays crucial role for skin development and its proper function | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | DHCR24 knockout mice, development of the epidermis, especially keratinization, is impaired, altered expression of filaggrin, loricrin, and involcrin, transepidermal water loss is markedly increased, impaired skin barrier function | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q8VCH6 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epidermis | abundantly expressed throughout the epidermis except for the stratum corneum and in hair follicles | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
desmosterol + NADPH | - |
Mus musculus | cholesterol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3beta-hydroxysterol-delta24 reductase | - |
Mus musculus |
DHCR24 | - |
Mus musculus |