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Literature summary for 1.3.1.71 extracted from

  • Neal, W.D.; Parks, L.W.
    Sterol 24(28) methylene reductase in Saccharomyces cerevisiae (1977), J. Bacteriol., 129, 1375-1378.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.3.1.71

Activating Compound

Activating Compound Comment Organism Structure
EDTA 5fold increase in enzyme activity Saccharomyces cerevisiae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0108
-
 ergosta-5,7,22,24(241)-tetraen-3beta-ol
-
 Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ergosta-5,7,22,24(241)-tetraen-3beta-ol + NADPH + H+ Saccharomyces cerevisiae
-
 ergosta-5,7,22-trien-3beta-ol + NADP+ trivial name ergosterol ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ergosterol + NADP+ = ergosta-5,7,22,24(241)-tetraen-3beta-ol + NADPH + H+ acts on a range of steroids with a 24(241)-double bond Saccharomyces cerevisiae
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ergosta-5,7,22,24(241)-tetraen-3beta-ol + NADPH + H+
-
 Saccharomyces cerevisiae ergosta-5,7,22-trien-3beta-ol + NADP+ trivial name ergosterol ?
ergosta-5,7,22-trien-3beta-ol + NADP+ trivial name ergosterol Saccharomyces cerevisiae ergosta-5,7,22,24(241)-tetraen-3beta-ol + NADPH + H+
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Saccharomyces cerevisiae

pH Range

pH Minimum pH Maximum Comment Organism
6.5 8.5
-
 Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Saccharomyces cerevisiae