Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | enzyme induction by 4-chlorobenzenesulfonic acid | Pseudomonas aeruginosa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-maleylacetate + NAD(P)H + H+ | Pseudomonas aeruginosa | - |
3-oxoadipate + NAD(P)+ | - |
r | |
2-maleylacetate + NAD(P)H + H+ | Pseudomonas aeruginosa RW41 | - |
3-oxoadipate + NAD(P)+ | - |
r | |
additional information | Pseudomonas aeruginosa | the enzyme is involved in degradation of 4-chlorobenzenesulfonic acid, 4CBSA, the major polar by-product of the chemical synthesis of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl) ethane, DDT, overview, 4-chlorobenzenesulfonic acid catabolic pathway, overview | ? | - |
? | |
additional information | Pseudomonas aeruginosa RW41 | the enzyme is involved in degradation of 4-chlorobenzenesulfonic acid, 4CBSA, the major polar by-product of the chemical synthesis of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl) ethane, DDT, overview, 4-chlorobenzenesulfonic acid catabolic pathway, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | O87612 | - |
- |
Pseudomonas aeruginosa RW41 | O87612 | - |
- |
Purification (Comment) | Organism |
---|---|
native enzyme partially by anion exchange chromatography | Pseudomonas aeruginosa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | the enzyme is only present when cells grow on 4-chlorobenzenesulfonic acid | Pseudomonas aeruginosa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0034 | - |
substrate 2-maleylacetate, crude enzyme extract | Pseudomonas aeruginosa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-maleylacetate + NAD(P)H + H+ | - |
Pseudomonas aeruginosa | 3-oxoadipate + NAD(P)+ | - |
r | |
2-maleylacetate + NAD(P)H + H+ | i.e. 3-hydroxymuconate | Pseudomonas aeruginosa | 3-oxoadipate + NAD(P)+ | - |
r | |
2-maleylacetate + NAD(P)H + H+ | - |
Pseudomonas aeruginosa RW41 | 3-oxoadipate + NAD(P)+ | - |
r | |
2-maleylacetate + NAD(P)H + H+ | i.e. 3-hydroxymuconate | Pseudomonas aeruginosa RW41 | 3-oxoadipate + NAD(P)+ | - |
r | |
additional information | the enzyme is involved in degradation of 4-chlorobenzenesulfonic acid, 4CBSA, the major polar by-product of the chemical synthesis of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl) ethane, DDT, overview, 4-chlorobenzenesulfonic acid catabolic pathway, overview | Pseudomonas aeruginosa | ? | - |
? | |
additional information | the enzyme is involved in degradation of 4-chlorobenzenesulfonic acid, 4CBSA, the major polar by-product of the chemical synthesis of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl) ethane, DDT, overview, 4-chlorobenzenesulfonic acid catabolic pathway, overview | Pseudomonas aeruginosa RW41 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
maleylacetate reductase | - |
Pseudomonas aeruginosa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD(P)+ | - |
Pseudomonas aeruginosa | |
NAD(P)H | - |
Pseudomonas aeruginosa |