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Literature summary for 1.3.1.3 extracted from

  • Brown-Grant, K.; Forchielli, E.; Dorfman, R.I.
    The DELTA4-hydrogenases of guinea pig adrenal gland (1960), J. Biol. Chem., 235, 1317-1320.
    View publication on PubMed
Search for more literature for 1.3.1.3

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Cavia porcellus 5829
-

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Cavia porcellus

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
 Cavia porcellus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
11beta,17alpha,21-trihydroxy-pregn-4-en-3,20-dione + NADPH
-
 Cavia porcellus 11beta,17alpha,21-trihydroxypregnan-3,20-dione + NADP+
-
 ?
11beta,17alpha,21-trihydroxy-pregn-4-en-3,20-dione + NADPH
-
 Rattus norvegicus 11beta,17alpha,21-trihydroxypregnan-3,20-dione + NADP+
-
 ?
17alpha,21-dihydroxy-pregn-4-en-3,20-dione + NADPH
-
 Cavia porcellus 17alpha,21-dihydroxy-pregnan-3,20-dione + NADP+
-
 ?
17alpha,21-dihydroxy-pregn-4-en-3,20-dione + NADPH
-
 Rattus norvegicus 17alpha,21-dihydroxy-pregnan-3,20-dione + NADP+
-
 ?
17alpha-methylestr-4-en-3-one + NADPH
-
 Cavia porcellus 17alpha-methylestran-3-one + NADP+
-
 ?
17alpha-methylestr-4-en-3-one + NADPH
-
 Rattus norvegicus 17alpha-methylestran-3-one + NADP+
-
 ?
17beta-hydroxyandrost-4-en-3-one + NADPH trivial name testosterone Cavia porcellus 17beta-hydroxy-5beta-androstan-3-one + NADP+
-
 ?
17beta-hydroxyandrost-4-en-3-one + NADPH trivial name testosterone Rattus norvegicus 17beta-hydroxy-5beta-androstan-3-one + NADP+
-
 ?
17beta-hydroxyestr-4-en-3-one + NADPH
-
 Cavia porcellus 17-hydroxyestran-3-one + NADP+
-
 ?
17beta-hydroxyestr-4-en-3-one + NADPH
-
 Rattus norvegicus 17-hydroxyestran-3-one + NADP+
-
 ?
androst-4-en-3,17-dione + NADPH
-
 Cavia porcellus 5beta-androstan-3,17-dione + NADP+
-
 ?
androst-4-en-3,17-dione + NADPH
-
 Rattus norvegicus 5beta-androstan-3,17-dione + NADP+
-
 ?
cortisone + NADPH + H+
-
 Cavia porcellus 5beta-17,21dihydroxy-pregnan-3,11,20-trione + NADP+
-
 ?
cortisone + NADPH + H+
-
 Rattus norvegicus 5beta-17,21dihydroxy-pregnan-3,11,20-trione + NADP+
-
 ?
deoxycorticosterone + NADPH
-
 Cavia porcellus pregnan-21-ol-3,20-dione + NADP+
-
 ?
deoxycorticosterone + NADPH
-
 Rattus norvegicus pregnan-21-ol-3,20-dione + NADP+
-
 ?
progesterone + NADPH + H+
-
 Cavia porcellus pregnan-3,20-dione + NADP+
-
 ?
progesterone + NADPH + H+
-
 Rattus norvegicus pregnan-3,20-dione + NADP+
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.5
-
-
 Cavia porcellus

Cofactor

Cofactor Comment Organism Structure
NADPH absolutely required Cavia porcellus
NADPH absolutely required Rattus norvegicus