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BRENDA support

Literature summary for 1.3.1.3 extracted from

  • Wilton, D.C.
    Is a Schiff base involved in the mechanism of the DELTA4-3-oxo steroid 5alpha- or 5beta-reductases from mammalian liver? (1976), Biochem. J., 155, 487-491.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Reaction

Reaction Comment Organism Reaction ID
5beta-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ mechanism, Schiff-base intermediate not involved Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Rattus norvegicus