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Literature summary for 1.3.1.24 extracted from

  • Mancuso, C.
    Biliverdin reductase as a target in drug research and development Facts and hypotheses (2021), Free Radic. Biol. Med., 172, 521-529 .
    View publication on PubMed

Application

Application Comment Organism
diagnostics peripheral biomarker for the early diagnosis of Alzheimer's disease Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P53004
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-

Source Tissue

Source Tissue Comment Organism Textmining
gastric fundus mucosal epithelial cells and endothelium of intramural vessels Homo sapiens
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Synonyms

Synonyms Comment Organism
Biliverdin reductase-A
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Homo sapiens

General Information

General Information Comment Organism
metabolism the enzyme catalyzes the reduction of heme-derived biliverdin into bilirubin, which is a powerful endogenous free radical scavenger Homo sapiens
physiological function the enzyme is involved in the pathogenesis of neurodegenerative, metabolic, cardiovascular and immune-inflammatory diseases as well as in cancer Homo sapiens