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Literature summary for 1.3.1.22 extracted from

  • Appell, R.A.
    Male lower urinary tract symptoms: treatment with alpha-blockers, 5-alpha-reductase inhibitors, antimuscarinics, or a combination (2007), Curr. Urol. Rep., 8, 370-372.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
dutasteride inhibitor of isoenzymes 5-alpha-reductase type 1 and type 2 Homo sapiens
finasteride 5 mg/day, selective inhibitor of isoenzyme 5-alpha-reductase type 2 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
testosterone + NADPH + H+
-
Homo sapiens 5alpha-dihydrotestosterone + NADP+ + H+
-
?

Synonyms

Synonyms Comment Organism
5-alpha-reductase type 1 isozyme Homo sapiens
5-alpha-reductase type 2 isozyme Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Homo sapiens