Literature summary for 1.3.1.22 extracted from

Matsuda, H.; Yamazaki, M.; Naruo, S.; Asanuma, Y.; Kubo, M.
Anti-androgenic and hair growth promoting activities of Lygodii spora (spore of Lygodium japonicum) I. Active constituents inhibiting testosterone 5alpha-reductase (2002), Biol. Pharm. Bull., 25, 622-626.

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Inhibitors

Inhibitors	Comment	Organism	Structure
asclepic acid	50% inhibition at 0.50 mM	Rattus norvegicus
ethinylestradiol	50% inhibition at 0.81 mM	Rattus norvegicus
linoleic acid	50% inhibition at 0.37 mM	Rattus norvegicus
additional information	not inhibitory: stearic acid	Rattus norvegicus
oleic acid	50% inhibition at 0.44 mM	Rattus norvegicus
palmitic acid	50% inhibition at 1.35 mM	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

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Release 2023.1 (January 2023)