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Literature summary for 1.3.1.22 extracted from

  • Span, P.N.; Smals, A.G.; Sweep, C.G.; Benraad, T.J.
    Rat steroid 5alpha-reductase kinetic characteristics: extreme pH-dependancy of the type II isozyme in prostate and epididymis homogenates (1995), J. Steroid Biochem. Mol. Biol., 54, 185-192.
    View publication on PubMed
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KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0011
-
 testosterone prostrate homogenate at pH 7 Rattus norvegicus
0.0025
-
 testosterone epidymis homogenate at pH 4.5 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epididymis
-
 Rattus norvegicus
-
prostate gland
-
 Rattus norvegicus
-

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5
-
 isozyme 2, high substrate concentration Rattus norvegicus
5.5
-
 isozyme 2, low substrate concentration, efficiency optimum Vmax/Km Rattus norvegicus