Literature summary for 1.3.1.21 extracted from

Hall, P.; Michels, V.; Gavrilov, D.; Matern, D.; Oglesbee, D.; Raymond, K.; Rinaldo, P.; Tortorelli, S.
Aripiprazole and trazodone cause elevations of 7-dehydrocholesterol in the absence of Smith-Lemli-Opitz Syndrome (2013), Mol. Genet. Metab., 110, 176-178.

Search for more literature for 1.3.1.21

Application

Application	Comment	Organism
medicine	screening of patients diagnosed for elevated 7-dehydrocholesterol levels identified three individuals affected with Smith-Lemli-Opitz Syndrome, and 22 with elevated 7-dehydrocholesterol levels in the absence of Smith-Lemli-Opitz Syndrome. Seven of these individuals showed no mutation in the gene encoding 7-dehydrocholesterol reductase. The medication history of these individuals revealed aripiprazole and trazodone as common medications to all the false positive results	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)