Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-(2-[1-(n-chlorocinnamyl) piperazin-4-yl] ethyl) benzoic acid | - |
Homo sapiens | |
4-(2-[1-(n-chlorocinnamyl) piperazin-4-yl] ethyl) benzoic acid | i.e. BM 15.766 non-competitive | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholesta-5,7-dien-3-beta-ol + NADPH | Rattus norvegicus | - |
cholesterol + NADP+ | - |
? | |
cholesta-5,7-dien-3-beta-ol + NADPH | Homo sapiens | defect in cholesterol biosynthesis cause multiple congenital, developmental and morphogenic anomalies, e.g. the Smith-Lemli-Opitz syndrome due to a gene mutation, overview | cholesterol + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholesta-5,7-dien-3-beta-ol + NADPH | - |
Rattus norvegicus | cholesterol + NADP+ | - |
? | |
cholesta-5,7-dien-3-beta-ol + NADPH | defect in cholesterol biosynthesis cause multiple congenital, developmental and morphogenic anomalies, e.g. the Smith-Lemli-Opitz syndrome due to a gene mutation, overview | Homo sapiens | cholesterol + NADP+ | - |
? | |
cholesta-5,7-dien-3beta-ol + NADPH | - |
Homo sapiens | cholesterol + NADP+ | - |
? | |
cholesta-5,7-dien-3beta-ol + NADPH | - |
Rattus norvegicus | cholesterol + NADP+ | - |
? | |
ergosta-5,7,22-trien-3beta-ol + NADPH | i.e. ergosterol | Rattus norvegicus | ergosta-5,22-diene-3beta-ol + NADP+ | - |
? | |
ergosta-5,7,22-trien-3beta-ol + NADPH | i.e. ergosterol | Homo sapiens | ergosta-5,22-diene-3beta-ol + NADP+ | i.e. brassicasterol | ? |
Synonyms | Comment | Organism |
---|---|---|
3-hydroxysterol DELTA7-reductase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens | |
NADPH | - |
Rattus norvegicus |