Cloned (Comment) | Organism |
---|---|
expression of cDNA in Saccharomyces cerevisiae and overexpression of recombinant protein Escherichia coli, sequence analysis | Arabidopsis thaliana |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | low activity | Arabidopsis thaliana | 5829 | - |
microsome | - |
Arabidopsis thaliana | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholesta-5,7-dien-3-beta-ol + NADPH | Arabidopsis thaliana | highly regiospecific for DELTA7-bond reduction, but wide substrate specificity | cholesterol + NADP+ | - |
? | |
ergosta-5,7-diene-3beta-ol + NADPH | Arabidopsis thaliana | also ergosta-5,24(28)-, ergosta-5,22,24(28)-eneols and cholesta-5,24- or cholesta-5,22,24-eneols can be formed in vivo in the mutants of Saccharomyces cerevisiae | ergosta-5-ene-3beta-ol + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | Q9LDU6 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholesta-5,7-dien-3-beta-ol + NADPH | highly regiospecific for DELTA7-bond reduction, but wide substrate specificity | Arabidopsis thaliana | cholesterol + NADP+ | - |
? | |
cholesta-5,7-dien-3beta-ol + NADPH | wide substrate spectrum | Arabidopsis thaliana | cholesterol + NADP+ | - |
? | |
ergosta-5,7,22-trien-3beta-ol + NADPH | i.e. ergosterol | Arabidopsis thaliana | ergosta-5,22-diene-3beta-ol + NADP+ | - |
? | |
ergosta-5,7-diene-3beta-ol + NADPH | - |
Arabidopsis thaliana | ergosta-5-eneol + NADP+ | - |
? | |
ergosta-5,7-diene-3beta-ol + NADPH | also ergosta-5,24(28)-, ergosta-5,22,24(28)-eneols and cholesta-5,24- or cholesta-5,22,24-eneols can be formed in vivo in the mutants of Saccharomyces cerevisiae | Arabidopsis thaliana | ergosta-5-ene-3beta-ol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
sterol DELTA7-reductase | - |
Arabidopsis thaliana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | no activity with NADH | Arabidopsis thaliana |