Literature summary for 1.3.1.20 extracted from

Tang, D.W.; Chang, K.W.; Chi, C.W.; Liu, T.Y.
Hydroxychavicol modulates benzo[a]pyrene-induced genotoxicity through induction of dihydrodiol dehydrogenase (2004), Toxicol. Lett., 152, 235-243.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	enzyme-mediated oxidative damage is involved in the hydroxychavicol and benzo[a]pyrene-induced toxic effects	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
carcinoma cell	human oral epidermal carcinoma cell line OEC-M1, enzyme expression is induced by pretreatment with hydroxychavicol	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	enzyme-mediated oxidative damage is involved in the hydroxychavicol and benzo[a]pyrene-induced toxic effects	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)