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Literature summary for 1.3.1.20 extracted from

  • Sato, K.; Nakanishi, M.; Deyashiki, Y.; Hara, A.; Matsuura, K.; Ohya, I.
    Purification and characterization of dimeric dihydrodiol dehydrogenase from dog liver (1994), J. Biochem., 116, 711-717.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
4-hydroxyacetophenone
-
Canis sp.
4-hydroxybenzaldehyde
-
Canis sp.
4-hydroxybenzophenone
-
Canis sp.
4-hydroxyphenylglyoxal
-
Canis sp.
ascorbate
-
Canis sp.
Cibacron blue
-
Canis sp.
isoascorbic acid
-
Canis sp.
p-chloromercuriphenyl sulfonate
-
Canis sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
39000
-
2 * 39000, SDS-PAGE Canis sp.
65000
-
gel filtration Canis sp.

Organism

Organism UniProt Comment Textmining
Canis sp.
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Canis sp.

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
Canis sp.
-
heart
-
Canis sp.
-
intestine
-
Canis sp.
-
kidney
-
Canis sp.
-
lens
-
Canis sp.
-
liver
-
Canis sp.
-
lung
-
Canis sp.
-
spleen
-
Canis sp.
-
testis
-
Canis sp.
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
5.65
-
purified enzyme Canis sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,3-heptanedione + NADPH
-
Canis sp. ?
-
?
2,3-hexanedione + NADPH
-
Canis sp. ?
-
?
2,3-pentanedione + NADPH
-
Canis sp. ?
-
?
3-deoxyglucosone + NADPH
-
Canis sp. ?
-
?
3-nitrobenzaldehyde + NADPH
-
Canis sp. 3-nitrobenzylalcohol + NADP+
-
?
4-nitrobenzaldehyde + NAD(P)H
-
Canis sp. 4-nitrobenzylalcohol + NAD(P)+
-
?
acetoin + NADP+
-
Canis sp. ?
-
?
camphorquinone + NAD(P)H
-
Canis sp. (1R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol + NADP+
-
?
cis-1,2-dihydrobenzene-1,2-diol + NAD(P)+ not: Canis sp. catechol + NAD(P)H
-
?
D-glyceraldehyde + NADPH
-
Canis sp. ?
-
?
D-lactaldehyde + NADP+
-
Canis sp. ?
-
?
diacetyl + NADPH
-
Canis sp. ?
-
?
dihydroxyacetone + NADPH
-
Canis sp. ?
-
?
ethyl pyruvate + NADPH
-
Canis sp. ethyl lactate + NADP+
-
?
L-glyceraldehyde + NADPH
-
Canis sp. ?
-
?
L-lactaldehyde + NADP+
-
Canis sp. ?
-
?
methyl pyruvate + NADPH
-
Canis sp. methyl lactate + NADP+
-
?
methylglyoxal + NADPH
-
Canis sp. ?
-
?
phenyl-1,2-propanedione + NADPH
-
Canis sp. ?
-
?
phenylglyoxal + NADPH
-
Canis sp. ?
-
?
pyridine-3-aldehyde + NADPH
-
Canis sp. ?
-
?
trans-1,2-dihydrobenzene-1,2-diol + NAD(P)+
-
Canis sp. catechol + NAD(P)H
-
r
trans-naphthalene dihydrodiol + NAD(P)+
-
Canis sp. ?
-
r
[1R,2R]-trans-cyclohexanediol + NADP+
-
Canis sp. ?
-
?

Subunits

Subunits Comment Organism
dimer 2 * 39000, SDS-PAGE Canis sp.

Synonyms

Synonyms Comment Organism
DD
-
Canis sp.
dihydrodiol dehydrogenase
-
Canis sp.

Cofactor

Cofactor Comment Organism Structure
NADP+
-
Canis sp.
NADPH
-
Canis sp.