Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5,6-Dihydropyrimidine | - |
Sus scrofa | |
NADPH | - |
Sus scrofa | |
Uracil | - |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.001 | - |
Uracil | - |
Sus scrofa | |
0.007 | - |
NADPH | - |
Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
thymine + NADPH | Sus scrofa | - |
dihydrothymine + NADP+ | - |
? | |
uracil + NADPH | Sus scrofa | - |
5,6-dihydrouracil + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
5,6-dihydrouracil + NADP+ = uracil + NADPH + H+ | nonclassical ping-pong mechanism | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
thymine + NADPH | - |
Sus scrofa | dihydrothymine + NADP+ | - |
? | |
uracil + NADPH | - |
Sus scrofa | 5,6-dihydrouracil + NADP+ | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Sus scrofa | |
NADPH | - |
Sus scrofa |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | inhibitory reactions between uracil, NADP+ and dihydrouracil | Sus scrofa |