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Literature summary for 1.3.1.13 extracted from
- Non-plastidic, tyrosine-insensitive prephenate dehydrogenases from legumes (2015), Nat. Chem. Biol., 11, 52-57.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | not inhibited by L-Tyr | Glycine max | |
| additional information | not inhibited by L-Tyr | Medicago truncatula |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.127 | - |
prephenate | at 37°C, pH not specified in the publication | Glycine max |  |
| 0.223 | - |
prephenate | at 37°C, pH not specified in the publication | Medicago truncatula | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| prephenate + NADP+ | Glycine max | - |
4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
| prephenate + NADP+ | Medicago truncatula | - |
4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Glycine max | - |
- |
- |
| Medicago truncatula | - |
- |
- |
| no activity in Arabidopsis thaliana | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | - |
Glycine max | - |
| leaf | - |
Medicago truncatula | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| prephenate + NADP+ | - |
Glycine max | 4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
| prephenate + NADP+ | - |
Medicago truncatula | 4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PDH1 | - |
Glycine max |
| PDH1 | - |
Medicago truncatula |
| TyrAp | - |
Glycine max |
| TyrAp | - |
Medicago truncatula |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 21.8 | - |
prephenate | at 37°C, pH not specified in the publication | Medicago truncatula | |
| 26.3 | - |
prephenate | at 37°C, pH not specified in the publication | Glycine max | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADP+ | - |
Glycine max | |
| NADP+ | - |
Medicago truncatula | |
kcat/KM [mM/s]
| kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 100 | - |
prephenate | at 37°C, pH not specified in the publication | Medicago truncatula | |
| 217 | - |
prephenate | at 37°C, pH not specified in the publication | Glycine max | |
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