Application | Comment | Organism |
---|---|---|
medicine | expression and alternative splicing of DIO mRNA is disturbed in renal cancer, possibly due to changes in expression of splicing factors SF2/ASF and hnRNPA1 | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
different splicing variants of DOI1 are cloned into the vector pGEM-T for sequencing, 11 variants are identified | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
selenium | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-thyroxine + AH2 | Homo sapiens | activation and deactivation of thyroid hormone | 3,5,3'-triiodo-L-thyronine + iodide + A + H+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P49895 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Homo sapiens | - |
renal cell carcinoma cell | ccRCC | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-thyroxine + AH2 | activation and deactivation of thyroid hormone | Homo sapiens | 3,5,3'-triiodo-L-thyronine + iodide + A + H+ | - |
r |
Synonyms | Comment | Organism |
---|---|---|
DIO1 | - |
Homo sapiens |
type 1 iodothyronine deiodinase | - |
Homo sapiens |