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Literature summary for 1.21.99.3 extracted from

  • Bessho, K.; Etani, Y.; Ichimori, H.; Miyoshi, Y.; Namba, N.; Yoneda, A.; Ooue, T.; Chihara, T.; Morii, E.; Aoki, T.; Murakami, M.; Mushiake, S.; Ozono, K.
    Increased type 3 iodothyronine deiodinase activity in a regrown hepatic hemangioma with consumptive hypothyroidism (2009), Eur. J. Pediatr., 169, 215-221.
    View publication on PubMed
Search for more literature for 1.21.99.3

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00000492
-
 3,3',5-triiodo-L-thyronine placental tissue Homo sapiens
0.00000522
-
 3,3',5-triiodo-L-thyronine hemangioma tissue Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Homo sapiens
-
 congential hypothyroidism
-

Source Tissue

Source Tissue Comment Organism Textmining
liver hepatic hemangioma, regrown Homo sapiens
-
placenta
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.00000005
-
 placental tissue Homo sapiens
0.0000006
-
 hemangioma tissue Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,3',5-triiodo-L-thyronine + AH2 assay at pH 7.0, 37°C Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
type 3 iodothyronine deiodinase
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 assay at Homo sapiens

Expression

Organism Comment Expression
Homo sapiens expression and activity of type 3 iodothyronine deiodinase are elevated in infantile hepatic hemangioma up