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Literature summary for 1.21.99.3 extracted from

  • Verhoelst, C.H.; Vandenborne, K.; Severi, T.; Bakker, O.; Zandieh Doulabi, B.; Leonard, J.L.; Kuhn, E.R.; van der Geyten, S.; Darras, V.M.
    Specific detection of type III iodothyronine deiodinase protein in chicken cerebellar purkinje cells (2002), Endocrinology, 143, 2700-2707.
    View publication on PubMed
Search for more literature for 1.21.99.3

Cloned(Commentary)

Cloned (Comment) Organism
isozyme type III, via RT-PCR from cerebellum mRNA, expression in bacteria Gallus gallus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome isozyme type III Gallus gallus
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 x * 30000, isozyme type III, SDS-PAGE Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3,3',5-triiodo-L-thyronine + AH2 Gallus gallus isozyme type III 3,3'-diiodo-L-thyronine + iodide + A + H+
-
 ?
3,3',5-triiodo-L-thyronine + AH2 Gallus gallus enzyme plays a critical role in regulating and maintaining the local 3,3',5-triiodo-L-thyronine content 3,3'-diiodo-L-thyronine + iodide + A + H+
-
 ?
3,3',5-triiodo-L-thyronine + AH2 Gallus gallus Hybro isozyme type III 3,3'-diiodo-L-thyronine + iodide + A + H+
-
 ?
3,3',5-triiodo-L-thyronine + AH2 Gallus gallus Hybro enzyme plays a critical role in regulating and maintaining the local 3,3',5-triiodo-L-thyronine content 3,3'-diiodo-L-thyronine + iodide + A + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-
Gallus gallus
-
 isozyme type III
-
Gallus gallus Hybro
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain isozyme type III Gallus gallus
-
cerebellar Purkinje cell isozyme type III Gallus gallus
-
cerebellum Purkinje cells Gallus gallus
-
cerebellum isozyme type III Gallus gallus
-
embryo
-
 Gallus gallus
-
liver embryonic Gallus gallus
-
liver isozyme type III Gallus gallus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Gallus gallus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,3',5-triiodo-L-thyronine + AH2 isozyme type III Gallus gallus 3,3'-diiodo-L-thyronine + iodide + A + H+
-
 ?
3,3',5-triiodo-L-thyronine + AH2 enzyme plays a critical role in regulating and maintaining the local 3,3',5-triiodo-L-thyronine content Gallus gallus 3,3'-diiodo-L-thyronine + iodide + A + H+
-
 ?
3,3',5-triiodo-L-thyronine + AH2 isozyme type III Gallus gallus Hybro 3,3'-diiodo-L-thyronine + iodide + A + H+
-
 ?
3,3',5-triiodo-L-thyronine + AH2 enzyme plays a critical role in regulating and maintaining the local 3,3',5-triiodo-L-thyronine content Gallus gallus Hybro 3,3'-diiodo-L-thyronine + iodide + A + H+
-
 ?

Subunits

Subunits Comment Organism
? x * 30000, isozyme type III, SDS-PAGE Gallus gallus