Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.21.3.3 extracted from

  • Steffens, P.; Nagakura, N.; Zenk, M.H.
    The berberine bridge forming enzyme in tetrahydroprotoberberine synthesis (1984), Tetrahedron Lett., 25, 951-952.
No PubMed abstract available
Search for more literature for 1.21.3.3

Inhibitors

Inhibitors Comment Organism Structure
dithioerythritol 50% inhibition at 4 mM Berberis beaniana
o-phenanthroline 50% inhibition at 0.006 mM Berberis beaniana

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00014
-
 (S)-reticuline
-
 Berberis beaniana

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
49000
-
 gel filtration Berberis beaniana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-reticuline + O2 Berberis beaniana
-
 (S)-scoulerine + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Berberis beaniana
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R,S)-laudanosoline + O2 specific for the (S)-enantiomer Berberis beaniana ? + H2O2
-
 ?
(S)-protosinomenine + O2
-
 Berberis beaniana ? + H2O2
-
 ?
(S)-reticuline + O2
-
 Berberis beaniana (S)-scoulerine + H2O2
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.9
-
-
 Berberis beaniana