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Literature summary for 1.20.99.1 extracted from

  • Radabaugh, T.R.; Aposhian, H.V.
    Enzymatic reduction of arsenic compounds in mammalian systems Reduction of arsenate to arsenite by human liver arsenate reductase (2000), Chem. Res. Toxicol., 200; 13, 26-30.
No PubMed abstract available

Activating Compound

Activating Compound Comment Organism Structure
additional information heat stable cofactor is required Homo sapiens
thiol required for activity, thiol requirement can be satisfied by dithiothreitol, stimulation by glutathione, thioredoxin or reduced lipoc acid is negligible compared to that of dithiothreitol Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
71800
-
gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0007
-
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arsenate + ?
-
Homo sapiens arsenite + ?
-
?