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Literature summary for 1.2.7.4 extracted from

  • Jeoung, J.; Dobbek, H.
    Structural basis of cyanide inhibition of Ni, Fe-containing carbon monoxide dehydrogenase (2009), J. Am. Chem. Soc., 131, 9922-9923.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
cyanide slow binding inhibitor of CODH Carboxydothermus hydrogenoformans

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ CODHII contains iron, the active site of CODH contains a [NiFe4S4OHx] cluster known as C-cluster Carboxydothermus hydrogenoformans
Ni2+ CODHII contains nickel, the active site of CODH contains a [NiFe4S4OHx] cluster known as C-cluster Carboxydothermus hydrogenoformans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CO + H2O + acceptor Carboxydothermus hydrogenoformans
-
CO2 + reduced acceptor
-
r

Organism

Organism UniProt Comment Textmining
Carboxydothermus hydrogenoformans Q9F8A8
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CO + H2O + acceptor
-
Carboxydothermus hydrogenoformans CO2 + reduced acceptor
-
r

Synonyms

Synonyms Comment Organism
CODHII
-
Carboxydothermus hydrogenoformans