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Literature summary for 1.2.5.2 extracted from

  • Vangnai, A.S.; Arp, D.J.; Sayavedra-Soto, L.A.
    Two distinct alcohol dehydrogenases participate in butane metabolism by Pseudomonas butanovora (2002), J. Bacteriol., 184, 1916-1924.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.5.2

Activating Compound

Activating Compound Comment Organism Structure
additional information induction by alcohols, overview, BOH is induced by butanol and butane. When induced with butane, the gene for BOH is expressed early Thauera butanivorans

Cloned(Commentary)

Cloned (Comment) Organism
gene boh, DNA and amino acid sequence determination and analysis Thauera butanivorans

Protein Variants

Protein Variants Comment Organism
additional information insertional disruption of boh affects, but not fully eliminates butane utilization in the mutant organism, the double boh/bdh mutant with both genes boh and bdh inactivated is unable to grow on butane or 1-butanol, but does, when grown in citrate and incubated in butane, develop butane oxidation capability and accumulates 1-butanol, overview Thauera butanivorans

Localization

Localization Comment Organism GeneOntology No. Textmining
periplasm BOH contains the periplasm 29-residue leader sequence Thauera butanivorans
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
67553
-
 x * 67553, BOH, calculated from sequence Thauera butanivorans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Thauera butanivorans the NAD+-independent PQQ alcohol dehydrogenase BOH (a quinoprotein) is linked to butane metabolism in conjunction with BDH (a quinohemoprotein) ?
-
 ?

Organism

Organism UniProt Comment Textmining
Thauera butanivorans Q9AGW3 1-butanol dehydrogenase, BOH; strain ATCC 43655, gene boh
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
butyraldehyde + 2,6-dichlorophenolindophenol
-
 Thauera butanivorans butanoate + reduced 2,6-dichlorophenolindophenol
-
 ?
additional information the NAD+-independent PQQ alcohol dehydrogenase BOH (a quinoprotein) is linked to butane metabolism in conjunction with BDH (a quinohemoprotein) Thauera butanivorans ?
-
 ?
propionaldehyde + 2,6-dichlorophenolindophenol 30% of the activity with 2-butanol Thauera butanivorans propanoate + reduced 2,6-dichlorophenolindophenol
-
 ?

Subunits

Subunits Comment Organism
? x * 67553, BOH, calculated from sequence Thauera butanivorans

Synonyms

Synonyms Comment Organism
BOH
-
 Thauera butanivorans
NAD+-independent, PQQ-containing alcohol dehydrogenase
-
 Thauera butanivorans

Cofactor

Cofactor Comment Organism Structure
additional information BOH contains no heme c Thauera butanivorans
pyrroloquinoline quinone BOH is a quinoprotein Thauera butanivorans